KarstBase a bibliography database in karst and cave science.
Featured articles from Cave & Karst Science Journals
Characterization of minothems at Libiola (NW Italy): morphological, mineralogical, and geochemical study, Carbone Cristina; Dinelli Enrico; De Waele Jo
Chemistry and Karst, White, William B.
The karst paradigm: changes, trends and perspectives, Klimchouk, Alexander
Long-term erosion rate measurements in gypsum caves of Sorbas (SE Spain) by the Micro-Erosion Meter method, Sanna, Laura; De Waele, Jo; Calaforra, José Maria; Forti, Paolo
The use of damaged speleothems and in situ fault displacement monitoring to characterise active tectonic structures: an example from Zapadni Cave, Czech Republic , Briestensky, Milos; Stemberk, Josef; Rowberry, Matt D.;
Featured articles from other Geoscience Journals
Karst environment, Culver D.C.
Mushroom Speleothems: Stromatolites That Formed in the Absence of Phototrophs, Bontognali, Tomaso R.R.; D’Angeli Ilenia M.; Tisato, Nicola; Vasconcelos, Crisogono; Bernasconi, Stefano M.; Gonzales, Esteban R. G.; De Waele, Jo
Calculating flux to predict future cave radon concentrations, Rowberry, Matt; Marti, Xavi; Frontera, Carlos; Van De Wiel, Marco; Briestensky, Milos
Microbial mediation of complex subterranean mineral structures, Tirato, Nicola; Torriano, Stefano F.F;, Monteux, Sylvain; Sauro, Francesco; De Waele, Jo; Lavagna, Maria Luisa; D’Angeli, Ilenia Maria; Chailloux, Daniel; Renda, Michel; Eglinton, Timothy I.; Bontognali, Tomaso Renzo Rezio
Evidence of a plate-wide tectonic pressure pulse provided by extensometric monitoring in the Balkan Mountains (Bulgaria), Briestensky, Milos; Rowberry, Matt; Stemberk, Josef; Stefanov, Petar; Vozar, Jozef; Sebela, Stanka; Petro, Lubomir; Bella, Pavel; Gaal, Ludovit; Ormukov, Cholponbek;
University of South Florida, Tampa
International Journal of Speleology, 2013, Vol 42, Issue 2, p. 147-153
The effects of UV light on the antimicrobial activities of cave actinomycetes
Rule Devon, Cheeptham Naowarat
Abstract:
The goal of this study was to determine whether actinomycetes isolated from a volcanic cave in western Canada could produce novel antimicrobial compounds against six multidrug- resistant pathogens when exposed to UV light. One hundred and seventy-six actinomycete strains isolated from Helmcken Falls Cave, Wells Gray Provincial Park, BC, were screened against six pathogens using the “plug assay” in UV light and no light conditions. Of the 176 strains tested, 100 or 57% of the cave actinomycete strains had antimicrobial activities against the pathogens in 124 different instances: 35 instances when exposed to UV and no light, 30 when exposed to UV light, and 59 instances when exposed to no light. The metabolites of six actinomycete strains also lost their antimicrobial activities when exposed to UV light. While the metabolites produced by these strains have yet to be determined, exposure to lighted environments may either deactivate or enhance the antimicrobial activities of cave actinomycete strains. This study represents a confirmation that cave actinomycetes are potential sources of novel antimicrobial compounds and also is the first report of the enhancement of antimicrobial activities of some cave bacteria by exposure to UV light. Further investigation of the role of UV light with respect to activation/deactivation of antimicrobial activities of cave actinomycetes is required.
The goal of this study was to determine whether actinomycetes isolated from a volcanic cave in western Canada could produce novel antimicrobial compounds against six multidrug- resistant pathogens when exposed to UV light. One hundred and seventy-six actinomycete strains isolated from Helmcken Falls Cave, Wells Gray Provincial Park, BC, were screened against six pathogens using the “plug assay” in UV light and no light conditions. Of the 176 strains tested, 100 or 57% of the cave actinomycete strains had antimicrobial activities against the pathogens in 124 different instances: 35 instances when exposed to UV and no light, 30 when exposed to UV light, and 59 instances when exposed to no light. The metabolites of six actinomycete strains also lost their antimicrobial activities when exposed to UV light. While the metabolites produced by these strains have yet to be determined, exposure to lighted environments may either deactivate or enhance the antimicrobial activities of cave actinomycete strains. This study represents a confirmation that cave actinomycetes are potential sources of novel antimicrobial compounds and also is the first report of the enhancement of antimicrobial activities of some cave bacteria by exposure to UV light. Further investigation of the role of UV light with respect to activation/deactivation of antimicrobial activities of cave actinomycetes is required.